This paper introduces self-centering energy dissipation brace into the cable-supported truss, and for the cable-supported truss with self-centering energy dissipation brace. This paper studies the seismic response of cable-supported truss combining the self-centering energy dissipation brace. First, the finite element model is constituted. Then, the inelastic time-history analysis method is used to analyze the vibration response under strong seismic excitation. The result shows that self-centering energy dissipation brace effectively improves the vibration performance and reduces the residual deformation. In addition, the parametric analysis is conducted to analyze the influence of the activation force, activation displacement and strength ratio on the vibration performance. Analytical results indicate that increasing the activation force can effectively control the residual deformation in horizontal direction; diminution of the brace strength ratio improves the self-centering performance, but reduces the energy dissipation capacity of brace; activation displacement has certain influence on peak displacement and minor effect on residual displacement; however, self-centering capacity declines with large activation displacement.