As the common equipment in petrochemical enterprises， pipe vibration brings serious risks to the safe operation of the equipment. Based on the principle of direct velocity feedback control， the control force is applied to the vibrating pipe system through the active damping device， which realizes the active control of the pipeline vibration. The stability of the control system is analyzed by the root locus method， the influence of the dynamic characteristics of the inertial actuator on the stability of the system is verified in the experiment， and the instability of the system is observed when the gain coefficient is too large. Using the acceleration level as the judging criteria， the control effects of the active damping device on pipeline vibration under different feedback gain coefficients are compared， the effective frequency range of the active damping device is also explored. The result shows that with the reasonable selection of the feedback gain coefficient， the active damping device can control the pipe vibration well in the linear working range of the actuator （20~50 Hz）， the maximum vibration control effect can reach 80%. Finally， the reference opinion of the design and use of the active damping device is put forward， which provides a way for the further improvement of the vibration control effect.