This research presented a piezoelectric pump with unsymmetrical slopes element (PPUSE) to overcome drawbacks existing in the common valveless piezoelec tric pumps with stream tubes which was used to create the unidirectional flow an d meanwhile the barriers to pump minimization. The type of piezoelectric pump ar ranged the unidirectional flow generating part: the unsymmetrical slopes element in the base of the chamber. A numerical modeling was conducted for the PPUWSE;the moving of piezoelectric vibrator was simulated by using user defined functio n (UDF) of the commercial software FLUENT12 and the flow field in the pump chamb er was analyzed by using the solve method of transient state NS functions based on turbulence model. As a result, the average flow rates of different slope ang les ranging from 20 to 70 degree were calculated, among which the maximum averag e flow rate reaches 0864 ml／min when the slope angle is 20 degree. Tests show that the maximum flow rate is 86ml／min. The feasibility of the pump was verif ied by both the simulation and the test.