Aiming at structure vibration problems of the station itself that caused by multiple unit passing through typical elevated railway station at high speed, the field measurement and simulation analysis methods are used. The multiple unit dynamic models and station′s finite element model are established respectively according to their structural parameters. The exciting force applied to rail of the station is obtained via dynamic simulation; Transient analysis type is defined, vibration response spectrum is got by forced vibration calculation. The correctness of the models is verified by contrasting with measured spectrum. On this basis, vibration propagation law and influence factors are emphatically analyzed; meanwhile, the simulation study is carried out. The research results provide some reference to vibration isolation problems of similar structural elevated railway station.