Large-span steel plates will produce vibration to affect the normal use under crowd load excitation. The vibration condition of large span steel structure floor of a railway station is analyzed under the crowd load. Tuned mass damper (TMD) system and fluid viscous dampers are installed in the middle span of steel beam located. The crowd load considers different person densities, different walking frequencies. Dynamical analysis and results prove that the vibration energy dissipation can effectively reduce the resonance response of the large-span floor structure. The mean ratio of vibration reduction rate comes up to 16.86％ of all cases, and the reduction rate of resonance case exceeds 38％ with crowd all synchronous model. The reduction rates are 15.50％ to 15.80％ at different density conditions with walk frequencies normal distribution model. This verifies the correctness of the load simulation method of walk frequency normal distribution model and provide theory basis for practical engineering design.