In order to research the influence of the fluid-structure coupling field for the strength and vibration parameters of the blade, the fluid dynamics and finite element method is used to analyze the compressor blade on the uniflow solid coupling. Through the interface between the softwares, the data transfer of the pressure field is realized, and the strength analysis and modal analysis of the calculation model after loading the aerodynamic force are completed. Meanwhile, the stress strain nephogram, the natural frequency, and the corresponding modal shapes of the big and small compressor blades are obtained. Further, the influence of the centrifugal force and the aerodynamic force on the stress and natural frequency are calculated and compared. The results show that the fluid-solid coupling has less effect on the blade structural strength and modal shapes. And through the frequency analysis, the resonance frequency of the blade is found out, so as to provide a basis for the optimization of the blade.