A collocated accelerometer sensing and piezoelectric actuating strategy is proposed for active vibration control. The target to be controlled is a clamped-clamped aluminum plate with acoustic excitation. An experimental system is designed to exert acoustic excitation on this plate. Based on the experimental modal test results, sensor and actuator locations are determined. Collocated accelerometer/piezoelectric patch and collocated piezoelectric patches are compared, and the acceleration sensing is selected due to good observability and controllability. According to positive position feedback (PPF) control law, a negative acceleration feedback (NAF) control law is proposed and the stability and control mechanism are analyzed. The acceleration level is selected as the judging criteria, and active control is targeted for two modal frequencies 64 Hz and 158 Hz simultaneously. The effectiveness of PPF control and the NAF control are compared. Experiment results show that the NAF control law can effectively suppress the vibration level of the aluminum plate by 11 dB, which is much more effective than the results from PPF control result.