A new type of large-thrust linear piezoelectric actuator is proposed. It achieves the goal of large-thrust and large-displacement output by accumulating the micro-amplitude of the piezoelectric stack through a kind of screw clamp mechanism. The driving mechanisms of the actuator and the key technology during the designing process are discussed in detail, including the design of the torque motor speed, the torsional stiffness of the flexible coupling, the design of the relationship between the nut and screw, and the best frequency phase of the stack after testing its performance. The length of the actuator is 140mm, and the maximum diameter is 45mm. The actuator weighs 0.7kg with a stroke of 40mm. The actuator exhibits a 130N blocked force when the speed of the torque motor is 300r/min and the frequency of the piezoelectric stack is 100Hz.