The methods and principles of the development of a virtual instrument based on mobile phone termination are discussed and implemented in light of the inconvenience of traditional detection and analysis instruments. First, Android native development kit (NDK) technology is proposed, and the Android platform programming technology and Bluetooth wireless transmission technology are researched. Then, the development of the cross platform virtual instrument on the Android system is studied, the virtual instrument system architecture is built, and the bearing diagnosis instrument is developed under the mobile platform. Finally, the field tests are constructed and compared with the simulation using LabVIEW. The results show that the instrument is both convenient and accurate.