The application of process damping in titanium alloy milling is studied. By using the implicit Runge-Kutta method, the indentation area and resistance caused by interference in the milling of typical titanium alloy is calculated, a nonlinear model that considers process damping is established, and the anti-vibration relief angle is designed to suppress chatter. The computed and experimental results indicate that the model is valid. Limit cutting depth at low speed can be significantly improved due to process damping, and the anti-vibration relief angle can strengthen the process damping effect and further expand the stable region.