In order to grasp the wind-induced dynamic characteristics of large antenna structures, a 110m fully steerable radio telescope to be built is used as a study platform and selected as the research object for various kinds of upwind profiles. Based on the wind tunnel test results of a rigid model, wind distribution characteristics of the reflector and the unfavorable wind angle are analyzed and discussed. On this basis, the nonlinear time-history method based on random vibration is used further analyze the wind-induced dynamic characteristics of the structure, and the wind vibration response features are summarized. The results indicate that the structure has a dense natural frequency distribution and is more flexible. Its wind vibration response is a narrow-band process. As elevation gradually increases, not only does the vibration energy increase, but the higher modes also contribute progressively to wind-induced vibration. The achievements above provide a more comprehensive wind load value reference for the telescope structure in its wind force proofing design.