The vibration and noise control strategy of the new developed particle vibration rehabilitation device is proposed. Firstly, the sound intensity of the prototype is tested, and it is confirmed that the thin-walled cylindrical barrel and particle layer are the main noise sources. Then, by finite element method (FEM), the vibration response of cylindrical barrel are calculated. After that，the frequency response curve of sound pressure level at cylindrical barrel field point is obtained, and the numerical simulation model of cylindrical barrel noise analysis is constructed and conformed by rig experiments. The vibration transmission path of the stainless steel cylinder barrel is improved by replacing the connection of the bottom of the barrel with a flange and rubber layer between the flange and the vibration platform. It is shown by simulation that the sound pressure level at the field point is reduced about 16.7 dB compared with the original prototype. And when the cylinder barrel material is changed to polymethyl methacrylate which is more damping and thicker, the field point sound pressure level will be expected to reduce about 28.2 dB，partly because the increase of the natural frequencies of the structure help to avoid resonance to take place. Finally, a test prototype with a polymethyl methacrylate barrel and a vibration isolation layer is set up. It is shown that the noise is reduced by about 15.2 dB(A) compared with the original prototype; and the noise is reduced about 3.5dB(A) if the barrel is filed with massage particles.