A new type of cantilever self-tuning vibration absorber with variable stiffness driven by piezoelectric material is designed, which is based on the principle that the natural frequency of the cantilever structure varies under different axial forces. The progressive optimization and genetic control algorithms are used to adjust the natural vibration frequency of the absorber in real time, and the dynamic simulation analysis is combined with the actual controlled system. Finally, the dynamic properties of the vibration absorber is further evaluated installed on wind tunnel aerodynamic models based on the effective vibration suppression of simulation analysis. The results show that the absorber can effectively attenuate vibration in a wide frequency range, and the highest damping effect reaches more than 40 dB, that has a better kinetic performance than other types of vibration controllers.