Abstract In order to study the dynamic response of asphalt pavement under the weak coupling of vehicle and road，a coupled model of 13-degree of freedom three-dimensional vehicle-rubber tire-asphalt pavement is established. Considering car body suspension，road surface roughness，and viscoelasticity of asphalt mixture，a central difference method is applied to solve the coupled equation，and simulation values are compared with actual vehicle-road weak coupled tests. By comparing with the test，the maximum error of the longitudinal shear strain is 5.74% between the calculated value and the experimental value. The contact is a three-way force state between the tire and the road surface，the three-way force and the vehicle suspension force generated by the dynamic load are greater than the moving dead load. Further，the longitudinal maximum compressive stresses of the upper layer， the middle layer，and the lower layer are 18.8%，11.8%，and 7.4% larger than the moving dead load，respectively. Similarly，the vertical maximum compressive stresses are 18.9%，19.8%，and 20.4% larger than the mobile dead load，and the transverse maximum compressive stresses are 10.2%，4.69%，and 2.1% larger，respectively.