A gas-liquid coupling excitation method is proposed to remove the pollutant from the inner wall of the pipeline by the high pressure gas-liquid pulse two-phase flow， which is alternated through the gas path and the liquid path. The dynamic model of the gas-liquid pulse two-phase flow is established， and its test system is developed. The simulation is carried out by using fluent module in specialized software ANSYS， where the k-ε two-equation turbulence model is considered， the volume of fluid （VOF） model is selected for the gas-liquid two-phase flow model， and the simple algorithm is used to solve the two-fluid control equations. Specifically， the pressure field， velocity field and flow regime of gas-liquid pulse two-phase flow is analyzed. Then， the pressure of the mixed fluid in the middle of the pipeline under different fluid pressures is measured by the pressure transmitter and the data acquisition card. The measured pressure signals are filtered and compared with the numerical simulation. It shows that the excitation pressure of the mixed fluid increases with the increasing mixed fluid pressure， and the measured pressure trend is basically consistent with the numerical simulation. It is also found that the excitation pressure of the mixed fluid gradually increased with the increasing ventilation time. The numerical simulation and experimental study reveal the kinetic characteristics of gas-liquid pulsed two-phase flow. So， it provides a theoretical basis and experimental study for the excitation pressure controllability of gas-liquid pulse two-phase flow.