It is of great significance to clarify the response of buried pipes under blasting vibration for the protection of the urban pipe network. In this paper， the blasting load of the ductile iron pipes after passing through the rock-soil interface is derived. Meanwhile， the Kelvin viscoelastic foundation model is utilized to simulate the pipe-soil interaction. Combined with the Timoshenko beam theory， the equilibrium differential equation of large diameter ductile iron pipes under the blasting vibration load is established in consideration of the effect of rotational inertia and shear deformation on the vibration characteristics of large diameter pipes. The vibration velocity of the pipe is solved by the Laplace transform. Moreover， the field vibration velocity of the pipe is obtained by field experiments and monitoring. The comparative analysis between field monitoring velocity and calculated velocity shows that the theory can accurately calculate the vibration response of the buried large diameter ductile iron pipeline under the blasting load of in bottom strata．