In order to reducing the vibration of pipeline system in low frequency domain， transfer path analysis （TPA） method is applied to separate the component of different transfer paths in this paper. The experimental results show that the synthetic results of vibration contribution of each path identified by the transfer path analysis method are consistent with the direct measurement results， which proves the correctness of the proposed method and test data. By analysis the vibration transfer paths and the input vibration power flow， it is found that the vibration of equipment in low frequency domain is transmitted mainly through raft bases. And the low frequency line spectrum is mainly caused by the coupling of piping system and cabin. This paper can give some valuable suggestions of the location and frequency optimize in active vibration control on pipeline system.